DEXERYL: an effective treatment for skin xerosis in sub-Saharan African patients

DEXERYL Emollient Cream

DEXERYL Emollient Cream

Statistically significant effectiveness proven in clinical studies on over 1000 patients. These studies were done against a placebo or comparator, providing the highest level of scientific evidence.

Discover the Emollient Cream

+ 80% significant reduction in skin dryness in children and adults 

Regular application of Dexeryl Emollient Cream twice a day to the body results in a significant reduction of 83.9% in skin dryness in children and 80.4% in adults within 2 months¹.

md_dexeryl_website-xerosis-sub-saharan-africa-patients​-results-graph 580x577 Évolution du score de sécheresse cutanée après 2 mois d’utilisation de DEXERYL Crème Émolliente. Graphique créé par Pierre Fabre.

-80.6%

itching in children after 2 months of treatment¹

of patients and doctors are satisfied with Dexeryl¹

1-Boralevi et al. Regression of cutaneous xerosis with emollient treatment in sub-Saharan African patients. Int. J. Dermatol. 2017

METHODOLOGY

Aim

To evaluate the effectiveness of an emollient cream (DEXERYL) on skin xerosis in African patients.  

Study

Longitudinal prospective multi-centre study. 7 countries: Benin, Burkina Faso, Cameroon, Côte d'Ivoire, Gabon, Mali and Senegal. 

Population

185 patients from sub-Saharan countries (56 children and 129 adults).

Dosage

2 applications daily.

Duration

8 weeks 

Primary evaluation criteria

Assess the evolution of xerosis (CRRS score) from baseline to week 8 (pre- and post-Dexeryl® treatment).

Secondary evaluation criteria

  • Change in CRRS score at week 4
  • Change in pruritus score at baseline, week 4 and week 8 (PO-SCORAD score)
  • Clinical improvement at week 4 and week 8 (CGI-A and PGIC scores)
  • Quality of life assessment at week 8 (DLQI score)
  • Compliance and tolerance 
  • Subjects' and practitioners' views on treatment

Tolerance

DEXERYL is safe and well-accepted.

Xerosis: causes, symptoms and treatments

Xerosis: causes, symptoms and treatments

Xerosis is the scientific term for dry skin. It is accompanied by other symptoms such as mild to significant flaking, fragile skin and thinning of the skin1. It is estimated that one in three people in France suffer from dry skin and that the frequency increases with age, affecting up to 75% of the elderly2. But what causes xerosis? What are the different forms? How do you relieve the symptoms?

Learn more about xerosis

Sources:  

1-Boralevi et al. Regression of cutaneous xerosis with emollient treatment in sub-Saharan African patients. Int. J. Dermatol. 2017

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