METHODOLOGY
Aim
To evaluate the effectiveness of an emollient cream (DEXERYL) on skin xerosis in African patients.
Study
Longitudinal prospective multi-centre study. 7 countries: Benin, Burkina Faso, Cameroon, Côte d'Ivoire, Gabon, Mali and Senegal.
Population
185 patients from sub-Saharan countries (56 children and 129 adults).
Dosage
2 applications daily.
Duration
8 weeks
Primary evaluation criteria
Assess the evolution of xerosis (CRRS score) from baseline to week 8 (pre- and post-Dexeryl® treatment).
Secondary evaluation criteria
- Change in CRRS score at week 4
- Change in pruritus score at baseline, week 4 and week 8 (PO-SCORAD score)
- Clinical improvement at week 4 and week 8 (CGI-A and PGIC scores)
- Quality of life assessment at week 8 (DLQI score)
- Compliance and tolerance
- Subjects' and practitioners' views on treatment
Tolerance
DEXERYL is safe and well-accepted.